Design of a bioreactor system: overview--Biological Systems and Media Design--Organism selection--Bacterial, yeast, and fungal cultures: effect of microorganism type and culture characteristics on bioreactor design and operation--Design, formulation, and optimization of media--Bioreactor Design--Fundamentals of bioreactor design--Stirred tank bioreactors--Pneumatically agitated bioreactors--Membrane reactors--Immobilized microorganism bioreactors--Immobilized animal cell bioreactors--Plant cell bioreactors--Photobioreactors--Bioreactor operation modes--Scale-up--Bioreactor Support Systems--Sterilization and containment--Bioreactor system supplies